ABSTRACT

INTRODUCTION. Dysmorphopsia/metamorphopsia is a visual disturbance characterized by subjective change in shape, size, colour or movement of external objects, due to pathology of eye or central nervous system. Owing to involvement of multiple structures in the origin of dysmorphopsia, differential diagnostics is important.

CASE PRESENTATION. We describe a clinical case of a patient with acute persistent metamorphopsia, associated with vaccination. 

RESULTS AND DISCUSSION. Ophthalmological, neurological examination of the patient as well as neurovisualization did not reveal structural lesions, which could cause acute disturbance of visual perception. Meanwhile the possibility of post-vaccination alterations without macro-structural changes in nervous system and visual path is confirmed by review of literature.

CONCLUSION. The phenomenology of neuro-ophthalmic disorders, associated with vaccination, in contrast with complications of  the infections themselves, are scarcely described in literature; the process of data accumulation continues. On the other hand, visual  distortion is also a rare phenomenon in clinical practice, stressful for a patient and causing diagnostic difficulties for the clinicians – neurologists and ophthalmologists, which is proved by this clinical case.

KEYWORDS: visual impairment, metamorphopsia, dysmorphopsia, vaccination

For citation: Starikova N.L., Busireva V.N., Drobakha V.E. Post-vaccination Dysmorphopsia: A Problem on the Border of Specialities. Case Report. Comorbidity Neurology. 2026; 3 (1): 50–55. https://doi.org/10.62505/3034-185x-2026-3-1-50-55 

*For correspondence: Natalia L. Starikova, Dr. Sci. (Med.), Professor, Professor of the Department of Integrative Medicine, Neurologist, E.A. Vagner Perm State Medical University, Perm, Russia, e-mail: nlsta@mail.ru.

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ADDITIONAL INFORMATION

Natalia L. Starikova, Dr. Sci. (Med.), Professor, Professor of the Department of Integrative Medicine, Neurologist, E.A. Vagner Perm State Medical University, Perm, Russia. E-mail: nlsta@mail.ru. ORCID: https://orcid.org/0000-0002-8350-7004

Veronika N. Busireva, Ph.D. Sci. (Med.), Head of Eye Microsurgery Department, Perm Regional Clinical Hospital "Order of the Badge of Honor", Perm, Russia. 

Viktor E. Drobakha, Associate Professor of the Department of Integrative Medicine, Radiologist, E.A. Vagner Perm State Medical University, Perm, Russia. ORCID: https://orcid.org/0000-0001-8523-2692

Author contributions. All authors confirm their authorship in accordance with the international ICMJE criteria (all authors made a significant contribution to the study conception, research design, and article preparation, read and approved the final version prior to publication). Special contributions: Starikova N.L. – conceptualization, methodology, investigation, writing – review & editing; Busireva V.N., Drobakha V.E. – investigation, formal analysis, data curation, writing – original draft.

Funding. This study was not supported by any external sources of funding.

Disclosure. The authors declare no apparent or potential conflicts of interest related to the publication of this article.

Informed consent for publication. All patients, and if it is impossible to review and sign, persons responsible for the patients (relatives, social workers, etc.) on behalf of the patients undergoing examination and participating in this study, signed informed consent.

The content is available under the Creative Commons Attribution 4.0 License.

©2026. Comorbidity Neurology