ABSRTACT

INTRODUCTION. Recent studies have shown that the appearance of multivessel coronary artery disease in acute coronary syndrome patients, as a manifestation of atherosclerotic arterial disease, is common in clinical practice, and these patients are at higher risk of subsequent acute cardiovascular events.

AIM. To analyze multi-vessel lesions of the coronary arteries in patients with atherosclerotic vascular lesions.

MATERIAL AND METHODS.  Among the examined patients were 43 patients who underwent coronary artery stenting and 16 patients who did not undergo stenting after acute coronary syndrome.

RESULTS AND DISCUSSION. The main indicators characterizing the development of risk in all examined patients varied widely, but on average were at an unsatisfactory level. In stented patients, the body mass index was 27.74+/-4.45 kg m2. While in non-stented patients, the body mass index  was 26.5+/-2.93 kg m2. At the same time, the blood glucose level in stented patients was slightly lower than in non-stented patients - 6.73 +/- 1.97 kg m2 and 8.88 +/- 6.14 kg m2. Low risk according to the Score 0-22 % scale was recorded in 18 examined patients, mainly stented. Average risk from 22 to 32 according to the Score scale was detected in 7 patients, also mainly in patients with stenting. And high risk, that is, above 32, was detected in 3 patients. A correlation was found between the blood glucose level and the age of patients, blood creatinine, interventricular septum, an inverse correlation with the glomerular filtration rate degree of stenosis of the left coronary artery and an inverse correlation between the number of stenotic coronary arteries with a high degree (more than 70%) of stenosis.

CONCLUCION. Coronary artery disease in patients with arterial atherosclerosis is characterized mainly by multivessel stenosis including narrowing of the coronary arteries by more than 70%, which is especially present in stented patients. The most pronounced stenosis was observed in the right coronary artery, left coronary artery and  anterior interventricular branch. At the same time, the blood glucose level reliably reflects stenosis of the right coronary artery and the thickness of the  interventricular septum.

KEYWORDS: arteries, atherosclerosis, myocardial infarction, cerebral stroke

For citation: Korolev V.A., Korsakova V.S. Multivessel Coronary Artery Disease in Patients with Atherosclerotic Vascular Disease. Comorbidity Neurology. 2025; 2 (3): 14-22. https://doi.org/10.62505/3034-185x-2025-2-3-14-22

*For correspondence: Vitaliy A. Korolev, Dr. Sci. (Med.), therapist-cardiologist, City Hospital No. 1 named after N.I. Pirogov, Sevastopol, Russia; Dzhankoy Interregional Hospital, Republic of Crimea, Crimea, Russia, e-mail: korolew71@yandex.ru

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ADDITIONAL INFORMATION

Vitaliy A. Korolev, Dr. Sci. (Med.), therapist-cardiologist, City Hospital No. 1 named after N.I. Pirogov, Sevastopol, Russia; Dzhankoy Interregional Hospital, Republic of Crimea, Russia. E-mail: korolew71@yandex.ru. ORCID: https://orcid.org/0000-0002-4150-1472

Victoria S. Korsakova, cardiologist, City Hospital 4, Kaliningrad, Russia. E-mail: tusyakorsakova@mail.ru

Author contributions The authors confirm that their authorship complies with the international ICMJE criteria (all authors made a significant contribution to the concept development, research, and preparation of the article, read and approved the final version before publication). Special contributions: Korolev V.A. – conceptualization, methodology, investigation, writing – review & editing; Korsakova E.S. – data curation, formal analysis.

Funding. This study was not supported by any external sources of funding.

Disclosure. The authors declare no apparent or potential conflicts of interest related to the publication of this article.

Informed consent to publication. All patients, and if it was impossible to review and sign, the persons responsible for the patients (relatives, social workers, etc.) signed an informed consent on behalf of the patients, who underwent the examination and participated in this study.

The content is available under the Creative Commons Attribution 4.0 License.

©2025. Vitaliy A. Korolev, Victoria S. Korsakova