ABSTRACT

INTRODUCTION. A lump in the throat (globus pharyngeus) is a common clinical disease, but its etiology remains unclear. This is a common clinical condition that usually lasts a long time, is difficult to treat and has a tendency to recur. Furthermore, due to the uncertain etiology of the lump in the throat, it remains difficult to establish standard investigation and treatment strategies for affected patients.

AIM. Systematize the available data on this problem and give rational recommendations for the management of patients with a similar symptom. 

CONCLUSION. The results of recent studies strongly suggest that gastro-esophageal reflux is the main cause of a lump in the throat, although this issue remains the subject of serious debate Numerous functional and organic causes have been proposed as potential sources of this sensation, such as impaired function of the upper esophageal sphincter (UES), esophageal motility disorders, structural diseases of the head and neck, as well as psychological factors.

KEYWORDS: lump in the throat, psychological factors, gastro-esophageal reflux, esophageal motility disorder, anxiety disorder, depression

For citation: Averchenkova A.A., Rachin A.P. Is the “Globus Pharyngeus” an Interdisciplinary Problem or A Patient’s Problem? Dispel Myths and Discuss Facts. A Review. Comorbidity Neurology. 2024; 1 (1): 60–68. https://doi.org/10.62505/3034-185x-2024-1-60-68 (In Russ.)

*For correspondence: Anastasia A. Averchenkova, Сand. Sci. (Med.), Neurologist, Reflexologist at the Multidisciplinary Medical Center “Clinic Park-M”, Smolensk, Russia, e-mail: clinicpark@mail.ru.

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ADDITIONAL INFORMATION
Anastasia A. Averchenkova, Сand. Sci. (Med.), Neurologist, Reflexologist at the Multidisciplinary Medical Center “Clinic Park-M”, Smolensk, Russia. E-mail: clinicpark@mail.ru. ORCID: https://orcid.org/0009-0003-9556-6794

Andrei P. Rachin, Dr. Sci. (Med.), Professor, President of the National Association of Experts in Comorbid Neurology, Moscow, Russia. E-mail: 7851377@gmail.com. ORCID: https://orcid.org/0000-0003-4266-0050 

Author contributions. All authors confirm the compliance of their authorship, according to international ICMJE criteria (all authors made a significant contribution to the development of the concept, research and preparation of the article, read and approved the final version before publication).

Funding. This study was not supported by any external sources of funding.

Disclosure. The authors declare that they have no competing interests.

The content is available under the Creative Commons Attribution 4.0 License.

©2024. Anastasia A. Averchenkova, Andrei P. Rachin