ABSTRACT

INTRODUCTION. About 40–60% of adult patients with complaints of abdominal pain suffer from functional gastrointestinal disorders. Currently, functional disorders of the gastrointestinal tract are associated with disturbances in the gut-brain interaction. Abdominal pain syndrome can be one of the leading manifestations of irritable bowel syndrome, functional dyspepsia syndrome and abdominal migraine. The exclusion of organic disorders of the gastrointestinal tract is an essential condition for the diagnosis of functional disorders. The basic principles of the treatment of functional abdominal pain syndrome should be aimed at correcting the psychological disorders involved in the formation of pain sensation.

MATERIAL AND METHODS. A review of the literature on this topic was conducted in the following databases: PubMed, Research Gate, Elsevier. The following phrases were used to search for literature: “Functional abdominal pain syndrome”, “Disorders of the gastrointestinal tract”.

DISCUSSION. Functional abdominal pain syndrome is a rather complex and ambiguous disease, which is based on complex cerebroabdominal connections (direct and reverse). This diagnosis is an exception, in other words, the diagnosis takes place when there are no obvious organic causes of the disease. The diagnosis of the functional abdominal pain syndrome is long and complex and includes various instrumental and laboratory methods of examination. Various methods are used in the treatment of the functional abdominal pain syndrome, ranging from non-drug methods (cognitive behavioral therapy, hypnotherapy) and ending with the use of medicines (antidepressants). It is important to keep in mind that the diagnosis and treatment of the functional abdominal pain syndrome requires the active participation of doctors of different specialties who are able to build a personalized diagnostic and therapeutic route using a biopsychosociocultural approach.

CONCLUSION. Functional abdominal pain syndrome attracts special attention in the diagnostic and therapeutic aspect. Although the exclusion of organic diseases is an essential condition for the diagnosis of the functional abdominal pain syndrome, it is necessary to take into account the connection and involvement of mental factors in the phenomenon of abdominal pain. Taking into account the complexity of the mechanisms involved in the development of functional gastrointestinal diseases, the basic principles of functional abdominal pain syndrome treatment should be aimed at correcting psychological disorders involved in the formation of pain sensation. 

KEYWORDS: functional abdominal pain syndrome, disturbances in the gut-brain interaction, interaction

For citation: Maksimova M.Yu., Sharov M.N., Zaitsev A.V., Prokofyeva Yu.S., Korsunskaya I.L., Rachin A.P., Rachin S.A., Parsamyan R.R. Functional Abdominal Pain Syndrome. A Review. Comorbidity Neurology. 2024; 1 (1): 44–51. https://doi.org/10.62505/3034-185x-2024-1-44-51 (In Russ.)

*For correspondence: Mikhail N. Sharov, Dr. Sci. (Med.), Professor of the Department of Nervous Diseases of the Faculty of Dentistry, Russian University of Medicine; Head of the Neurology Department at “City Clinical Hospital S.I. Spasokukptskogo”, Moscow, Russia, e-mail: 6112286@mail.ru.

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ADDITIONAL INFORMATION
Marina Yu. Maksimova, Dr. Sci. (Med.), Prof., Head of the 2nd Neurology Department, Research Center of Neurology, Moscow, Russia. Е-mail: ncnmaximova@mail.ru. ORCID: https://orcid.org/0000-0002-7682-6672

Mikhail N. Sharov, Dr. Sci. (Med.), Professor of the Department of Nervous Diseases of the Faculty of Dentistry, Russian University of Medicine; Head of the Neurology Department, City Clinical Hospital S.I. Spasokukptskogo, Moscow, Russia. E-mail: 6112286@mail.ru. ORCID: https://orcid.org/0000-0001-9634-346X

Andrey V. Zaitsev, Dr. Sci. (Med.), Professor of the Department of Urology, Russian University of Medicine, Moscow, Russia. Е-mail: zaitcevandrew@mail.ru. ORCID: 0000-0003-3044-1424

Yulia S. Prokofyeva, Graduate Student of Neurology Department, Russian University of Medicine, Moscow, Russia. E-mail: pryulek@yandex.ru. ORCID: https://orcid.org/0000-0003-4454-7174

Irina L. Korsunskaya, Cand. Sci. (Med.), urologist, City Clinical Hospital S.I. Spasokukptskogo, Moscow, Russia. E-mail: Korsunskayai@mail.ru. ORCID: https://orcid.org/0000-0002-7822-9062

Andrei P. Rachin, Dr. Sci. (Med.), Professor, President of the National Association of Experts in Comorbid Neurology, Moscow, Russia. E-mail: 7851377@gmail.com. ORCID: https://orcid.org/0000-0003-4266-0050

Sergei A. Rachin, Executive Director of the National Association of Experts in Comorbid Neurology, Moscow, Russia. E-mail: Rachin.sergei@gmail.com. ORCID: https://orcid.org/0000-0001-9771-4621

Ruzanna R. Parsamyan, Cand. Sci. (Med.), Associate Professor of the Department of Neurology named after. K.N. Tretyakova, Senior Researcher at the Department of Basic Research in Neurocardiology, Research Institute of Cardiology, Saratov State Medical University, Head of Clinic Pain, Saratov, Russia. E-mail: kvl.prr@mail.ru. ORCID: https://orcid.org/0000-0002-6509-5958

Author contributions. All authors confirm the compliance of their authorship, according to international ICMJE criteria (all authors made a significant contribution to the development of the concept, research and preparation of the article, read and approved the final version before publication). Prokofieva Yu.S., Rachin S.A., Korsunskaya I.L., Parsamyan R.R. — searched for suitable literature to create this review; Maksimova M.Yu., Sharov M.N., Rachin A.P., Zaitsev A.V. — correcting the text in accordance with the basic requirements of writing a review.

Funding. This study was not supported by any external sources of funding.

Disclosure. The authors declare that they have no competing interests.

The content is available under the Creative Commons Attribution 4.0 License.

©2024. Marina Yu. Maksimova, Mikhail N. Sharov, Anrey V. Zaitsev et al.