ABSTRACT

INTRODUCTION. Cardiovascular autonomic neuropathy is one of the most common and serious complications of diabetes mellitus, characterized by damage to components of the autonomic nervous system responsible for regulating the work of the heart and blood vessels.

AIM. To conduct a review of literature sources of domestic and foreign authors considering the issues of etiology, pathogenesis, clinical features and diagnostics of cardiovascular manifestations in diabetic autonomic neuropathy.

MATERIAL AND METHODS. A review of literature sources in Russian and English for the period 2014-2024 was conducted, the RSCI and PubMed databases were used.

RESULTS AND DISCUSSION. The article discusses the main aspects of the etiopathogenesis of cardiovascular autonomic neuropathy, including the influence of long-term course of diabetes mellitus and insufficient compensation of blood glucose levels. Clinical and epidemiological features of this condition are described, including a variety of symptoms and their significance for diagnosis. Particular attention is paid to methods of diagnosing cardiovascular autonomic neuropathy, which include assessment of clinical manifestations, laboratory tests and specialized studies. The importance of early detection and initiation of treatment to prevent disease progression and improve the quality of life of patients is emphasized.

CONCLUSION. Early detection and treatment cardiovascular autonomic neuropathy play a key role in preventing disease progression and improving patients’ quality of life. Particular attention should be paid to improving patient compliance, including precise adherence to doctor’s orders, diet, and healthy lifestyle.

KEYWORDS: diabetes mellitus, diabetic neuropathy, autonomic neuropathy, cardiovascular manifestations

For citation: Raevskaya A.I., Zinchenko D.A., Kovaleva O.D., Vyshlova I.A. Cardiovascular Autonomic Neuropathy: Etiopathogenesis, Clinical and Epidemiological Features, Diagnostic Methods: a Review. Comorbidity Neurology. 2024; 1 (4): 82-88. https://doi.org/10.62505/3034-185x-2024-1-4-82-88

*For correspondence: Anastasia I. Raevskaya, Assistant of the Department of Neurology, Neurosurgery and Medical Genetics, Stavropol State Medical University, Stavropol, Russia. E-mail: nastya_raevskaya96@mail.ru

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ADDITIONAL INFORMATION

Anastasia I. Raevskaya, Assistant of the Department of Neurology, Neurosurgery and Medical Genetics, Stavropol State Medical University, Stavropol, Russia. E-mail: nastya_raevskaya96@mail.ru. ORCID: https://orcid.org/0000-0002-4084-3307

Daniil A. Zinchenko, Student, Stavropol State Medical University, Stavropol, Russia. E-mail: Daniel.Zz@yandex.ru. ORCID: https://orcid.org/0009-0000-0335-1488

Olga D. Kovaleva, Student, Stavropol State Medical University, Stavropol, Russia. E-mail: olg.kovalyova2010@yandex.ru. ORCID: https://orcid.org/0009-0001-9907-5912

Irina A. Vyshlova, Dr. Sci. (Med.), Professor of the Department of Neurology, Neurosurgery and Medical Genetics, Stavropol State Medical University, Stavropol, Russia. E-mail: irisha2801@yandex.ru. ORCID: https://orcid.org/0000-0001-9187-8481

Author contribution.  All authors confirm the compliance of their authorship, according to international ICMJE criteria (all authors made a significant contribution to the development of the concept, research and preparation of the article, read and approved the final version before publication). Raevskaya A.I. – formation of ideas, formulation and development of key goals and objectives; Zinchenko D.A. – analysis of literary sources, article design; Kovaleva O.D. – analysis of literary sources; Vyshlova I.A. – preparation and editing of the text, approval of the final version of the article.

Funding. This study was not supported by any external sources of funding.

Disclosure. The authors declare that they have no competing interests.

The content is available under the Creative Commons Attribution 4.0 License.

©2024. Anastasia I. Raevskaya, Daniil A. Zinchenko, Olga D. Kovaleva, Irina A. Vyshlova